Cancer Research Clinical Trials for treatment Lung Cancer in Women

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src="images/0.gif" width="1" height="1" alt="" border="0"></td> </tr> </table> </td> <td> </td> <td valign="TOP" class="a"> <br> <br> <table width="100%" border="0" class="a" cellpadding="0" cellspacing="0"> <tr valign="top"> <td colspan="2"> <h2>Lung Cancer Clinical Trial - PGT307 </h2> <h1>XYOTAX (paclitaxel poliglumex, CT-2103) in combination with carboplatin for the treatment of chemotherapy-naive advanced non-small cell lung cancer (NSCLC) in women with estradiol greater than 30 pg/mL </h1> <h1>Would you like more information?</h1> Please email <a href="mailto:info@askarm.com">Medical Information Inquiries</a>, or from the U.S. call 1-800-715-0944 for more information about this trial.<br> <br> Find the cancer research <a href="prod_frame-ctri-lung-307loc.htm">clinical trial location in the United States nearest you. ></a><br> <br> <table width="100%" border="0"> <tr> <td width="27%"><img src="images/prod_307vid.jpg" alt="Clinical trial for lung cancer in women" width="108" height="105"></td> <td width="73%" valign="middle"><strong>CTI Medical Director, Jay Umbreit, M.D.</strong> discusses the PGT307 clinical trial for women with non-small cell lung cancer and normal estrogen levels in this 9-minute video.</td> </tr> <tr> <td colspan="2"><a href="video/CT2103AVI.avi" target="_blank">View Windows Media Player video></a></td> </tr> <tr> <td colspan="2"><a href="video/CT2103QuickTimeSmall.mov" target="_blank">View QuickTime video></a></td> </tr> <tr> <td colspan="2"><a href="video/CT2103iPod.m4v">Download iPod video ></a></td> </tr> </table> <h1>What is XYOTAX (CT-2103)?</h1> XYOTAX™ (Zi-o-taks) is a biologically-enhanced chemotherapeutic that links paclitaxel, the active ingredient in Taxol®, to a biodegradable polyglutamate polymer, which results in a new chemical entity. <a href="products_pgtxl.htm" target="_parent">More >></a></p> <h1>How is this lung cancer study conducted?</h1> This is a multinational, phase III open-label study of patients randomized to one of two arms.<br> <br> The primary objective of this study is to compare the overall survival of patients randomized to the CT-2103/carboplatin arm to that of patients randomized to the comparator arm, paclitaxel/carboplatin. Seconday objectives are to compare the progression-free survivial, disease control, clinical benefit, response rate, quality of life, and the safety and tolerability of the treatment arms. <br> <h1>Who can participate in this lung cancer clinical trial?<br> </h1> </td> </tr> <tr valign="top"> <td></td> <td>Adult women with histologically- or cytologically-confirmed diagnosis of advanced NSCLC with measurable or nonmeasurable disease</td> </tr> <tr valign="top"> <td></td> <td>Baseline estradiol greater than 30 pg/mL (women on hormone replacement therapy are allowed) </td> </tr> <tr valign="top"> <td></td> <td>Performance status 0, 1, or 2 </td> </tr> <tr valign="top"> <td width="3%">  </td> <td width="97%">No prior chemotherapy for NSCLC </td> </tr> <tr valign="top"> <td width="3%">  </td> <td width="97%">Patients must have either recurrent disease following radiation or surgery, stage IIIB disease in patients who are not candidates for combined modality therapy, or stage IV disease </td> </tr> <tr valign="top"> <td width="3%">  </td> <td width="97%">Those patients with known brain metastases must have recovered from therapy for their CNS metastases and must have stable neurologic function for at least 2 weeks before randomization. </td> </tr> <tr valign="top"> <td width="3%">  </td> <td width="97%">Adequate bone marrow, renal, hepatic, and cardiac function</td> </tr> <tr valign="top"> <td></td> <td>Other criteria that the study physician will evaluate </td> </tr> </table> <p><br> <font class="cr">Taxol® is a registered trademark of Bristol-Myers Squibb Co. <br> <br> Posted Nov. 28, 2007 </font><br> <br> <font class="cr">Copyright © 2004-2007 Cell Therapeutics, Inc., Seattle, WA, USA. All rights reserved. "Making cancer more treatable" is a registered mark of CTI. </font> <br>  </p></td> <td width="50"><img src="images/0.gif" width="5" height="128" alt="" border="0"></td> </tr> <tr> <td width="270"><img src="images/0.gif" width="270" height="1" alt="" border="0"></td> <td width="247"><img src="images/0.gif" width="50" height="1" alt="" border="0"></td> <td width="203"><img src="images/0.gif" width="400" height="1" alt="" border="0"></td> <td width="50"><img src="images/0.gif" width="50" height="1" alt="" border="0"></td> </tr> </table> </body>